Drugs & Individual Behavior
400:170g 
Dr. Linda L. Walsh

Spring, 2009
9:30 T Th   MSH 37

Table of Contents
  Requirements/Assignments      Grading Scale      MC Keys
Links to other Walsh Pages    Meet My Family    A sample of my garden    Highlights of 2008

 
PROFESSOR:
Dr. Linda L. Walsh

Office: Baker 441     Office Hours: 11:00 MWF; 
Mailbox: Baker 334   other times by appointment; drop-bys welcome.

Phone: 273-2690      Email: walsh@uni.edu 
Course online syllabus at: http://www.uni.edu/walsh/drugs99.html 
Drug Resources on the Web
Pharmacology Dictionary
Pharmacology Glossary
Street Drug Slang Terms
Drug Use Nationwide
Nonprescription Drugs
RxList
Medications
Healthtouch Drug Info
RXmed
Drug InfoNet
Web of Addictions
Alcoholics Anonymous
Online AA Resources
Narcotics Anonymous
Tobacco Control Archives
FDA    FDA News
Drug Enforcement Agency News
SAMHSA National Clearinghouse for Alcohol & Drug Information
Drug Interaction Checker
Class Schedule & Reading Assignments
Chapter numbers refer to our text:  A Primer of Drug Action (10th Edition,Worth Publishing) by Robert Julien
Underlined text refers to World Wide Web documents,easily accessed from our online syllabus at
http://www.uni.edu/walsh/drugs99.html
Lectures draw broadly from many sources so everything we cover will not be found in the text.
Tentative Schedule
Date Day Topic Reading Assignment
01/13  T Introduction to Drugs 
Pharmacists' Right to Refuse to Fill Prescriptions?
Pharmacy Refusal Project - Protecting A Woman's Right to Medication
FYI: 2 major national studies of drug use: 
Monitoring the Future     National Survey on Drug Use and Health
Syllabus; Chapter 1 thru p.13 Studylist for Chapter 1
FDA's Tips for Taking Medicines
Placebo Effect: Power of the Sugar Pill
Generic vs. Brand-Name?
01/15 TH Pharmacokinetics: How Drugs Move into, Around and 
Eventually Out of Your Body; 
Food-Drug & Drug-Drug Interactions 
Lecture Outline 1
US Pharmacist Overview of Drug Interactions
Pages 13-22
Food and Drug Interactions ; Grapefruit Juice Effect
Prescription Forms   Reading a Prescription Label 

Abbreviations Used in Prescriptions
01/20 T Drug Dose & Individual Differences in Drug Effects; 
Side Effects and Adverse Effects
Drug Safety and Effectiveness: No Drug is Completely Safe
Want to learn more about Anaphylaxis?      Wikipedia:Dose-Response
Chapter 2 Studylist for Chapter 2
Reporting Adverse Reactions 
How to Report Adverse Events 
Anaphylaxis FDA's Tips for Taking Medicines

 
01/22 TH Watch Out for Medication Errors
Medication Error Example: ADHD Kids Getting Methadone by Mistake
Too Much Marketing of Drugs??
Big Bucks - Big Pharma and Advertising
The Truth About Drug Companies
Avoiding Medication Errors    Med Errors Project 
Drug Names Causing Med Errors
Drug Interaction Checker

Start working on Assignment 1 for Jan 29
 
01/27 T Introduction  to Your  Nervous System 
Neurotransmitters & Their ReceptorsAll Psychoactive Drugs Exert Their Effects:
Neurotransmitters & Their Receptors 
Drug Effects on Messages in the Nervous System 
Chapter 3, this handout and these websites:
Basic Brain Areas    Print this handout to study
Autonomic Nervous System
The Synapse    Neurotransmitters
Studylist for Chapter 3
01/29 TH Assignment 1 Due
Review your notes so you can ask questions in preparation for our first exam
Don't miss class today!
02/03  T Test 1!!!

02/05
 TH Major Stimulants: Cocaine 
Helping patients beat cocaine addiction
Stimulants Outline
Chapter 7 Studylist for Chapter  7
Addiction's Path 
Effects of Cocaine in the Brain
Self-Test for Cocaine Addiction
02/10  T Stimulants: Amphetamines
Multimodal Treatment Study of Kids with ADHD 
Practice Parameter for the Use of Stimulant Medications..
Meth Addiction and Treatment    Crystal Meth Anonymous             
Methamphetamine 
Methcathinone
02/12  TH Stimulants: Caffeine & Its Relatives

Red Bull
  Caffeine/Nicotine Notes
Chapter 8  Studylist for Chapter 8
Neuroscience Resources for Kids - Caffeine
Adenosine And Sleep
Caffeine FAQ   Caffeine Content in Products
Exploring Chocolate   Caffeine Calculator
02/17  T Stimulants: Nicotine Nicotine and the Brain
ISAIC - Outside Resources-Tobacco
The QuitNet - Quit Smoking Resource
Drug therapy to aid in smoking cessation
02/19
 TH Introduction to CNS Depressants; Barbiturates p. 51; Chapter 5 thru p.94
02/24
 T CNS Depressants Continued: 
Benzodiazepines and Newer Drugs 
Barbiturate and Benzodiazepine Lecture Notes
Chapter 6  Barb/Benz Studylist
DEA-Rohypnol
GHB
02/26
 TH Test 2 (on Chaps 5,6,7,& 8) How to Get Into Pharmaceutical Sales
Pharmaceutical Sales
03/03
 T Alcohol: A Classic Depressant 
Select a brand name prescription medication for Assignment 2
Introduction to the PDR    Wikipedia: Physicians' Desk Reference description
Chapter 4  Studylist for 4
BAC Chart
Alcohol-Drug Interactions
Alcohol Self-Assessment
College Students & Drinking    Drinking 101


Midterm Grades Due

03/05
 TH Alcohol Continued; Inhalants
Grad Students: Submit your paper topic with an initial PsychINFO search
Alcohol Powerpoint
Inhalant Powerpoint
What is Alcoholics Anonymous?
Fact Sheet - FAS     NOFAS
12 Steps of Alcoholics Anonymous
Rational Recovery Center
Factline on Inhalants
03/10  T Narcotic Analgesics 
Assignment 2 due
Chapter 9
Opioids
Oxycodone
03/12
 TH Treatment of Narcotic Addiction 
Narcotics Notes 
Treatment of Addiction
Chap 9 Studylist


SPRING BREAK!!

03/24  T OTC Analgesics and Other Psychoactive OTCs 
Look up Nonprescription and Herbal Products
OTC powerpoint
Heading Off Migraine Pain
Chapter 10  Over the Counter Labeling Changes
Popular Uses of Aspirin  'An Aspirin a Day...'
Herbal Products--What You Should Know 
  • FDA Bans Ephedra Products 
  • Herbal Adverse Effects and Drug Interactions
    An FDA Guide to Dietary Supplements
    Supplements Associated with Illnesses and Injuries





    03/26  TH Herbal/Natural Remedies
    Herbal Powerpoint
    Chapter 20  Chap 10 Studylist
    Herbal Products--What You Should Know
    Herbal Adverse Effects and Drug Interactions
    An FDA Guide to Dietary Supplements
    Supplements Associated with Illnesses and Injuries
    03/31
     T
    Steroids
    Powerpoint Outline
    Chapter 14
    Andro Removed From Market
     04/02
     TH
    Test 3

    04/07
     T Psychotherapeutic Drugs: Antidepressants
    Depression in Children and Adolescents
    List of Brand & Generic Names of Psychiatric Medications
    Diagnosis & Management of Depression -- Monograph No. 2, 2000
    STAR*D (Sequenced Treatment Alternatives for Depression)
    Antidepressant Powerpoint
    Grad Students - Turn in 6 articles
    Chapter 15
    Drugs Commonly Prescribed for Depression 
    Newer Pharmacotherapies 
    Role of Placebo Effect in Antidepressant Action
    Social Phobia's Traumas and Treatment
    St. John's Wort
    04/14
     T Mood Stabilizers

    Assignment 3 Due

    Chapter 16
    Management of Bipolar Disorder
    Serotonin Syndrome
    04/16
     TH Antipsychotics
    CATIE Study of Effectiveness
    CUTLESS Study of Effectiveness
    Discussion of CUTLASS1 Study
    On the other side...      Another opinion
    Antipsychotics Powerpoint
    Chapter 17
    Extrapyramidal side effects 
    Tardive Dyskinesia
    04/21
     T Cannabis 

    Cannabis Powerpoint

    Chapter 11 
    The Brain's Stash   
    The Marijuana Anonymous Home Page
    04/23
    TH
    Cannabis continued Cannabis and Infertility      Cannabis and Cancer
    NORML News
    04/28
     T Classic Psychedelics Chapter 12
    Is LSD Safe? (from the Star Tribune)
    04/30
     TH Psychedelics continued 
    Lecture Outline
     

    ACh Related Hallucinogens
    05/07
     TH Final Exam 
     
    Studylist 4

    "How much of this stuff will be on the exam?"

        Yes, this course has a lot of assigned links, which have a lot of links, which have a lot of links . Relax, some of these links are images, study aids, or brief examples to help you learn class material. Only a portion of them are "readings". Many of the web links I will actually use as part of lecture. Feel free to go beyond what's assigned however - that's often how you'll find what in this drugs course what is most personally meaningful or useful to you. What you find will reinforce the textbook and lectures, and so it will also help you to do better on the exams. The more ways that you interact with the vocabulary, concepts and findings we will be discussing, the better your memory and understanding of the material will be.
        Which brings us to the fact that although drugs and behavior is an interesting and important topic, it is not an easy topic to master. We will be covering dozens of drug names, hundreds of drug effects on behavior, on the body or impacting on society. Many of you will have difficulty with our brief discussions of how the drugs actually change nervous system functioning. To remember the details of this course really requires active study techniques on your part!! I can almost guarantee you that attending class and reading the book won't be enough to earn top grades in this class. It takes some active drilling and doing, some intentional repeated studying of material (rather than one cram session) to keep the facts straight. I strongly recommend 1) actively taking condensed notes and/or making flashcards for each chapter we cover. Try filling out this table as you read each chapter. If you don't find all the information in the book, bring your tables to class. Lecture is most important and will pull in information from sources other than our text. We also will skip some of the detail in the book (but you have to be in class to know what you are responsible for). Drug information is worth the effort because I think you will use what you learn for the rest of your life.

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    Course Requirements

         Realizing that this course draws students from many different majors and with varying commitments outside of the class, I have tried to design a flexible set of assignments that gives you some freedom of choice. A few assignments I consider important learning experiences for all students. These are labeled REQUIRED below. Other assignments may be of interest to students with particular career goals/interests or to students who prefer to have a greater percentage of their grade based on assignments and a smaller percentage of their grade depending on tests. Many students feel like they have more control over how well they do on assignments vs the uncertainty of how well they might do on exams. These assignments are labeled OPTIONAL below. Note that OPTIONAL does not mean extra credit: if you choose to do optional assignments your "points possible" increases, the relative importance of tests decreases. In the end your grade will be based on the percentage of points you earned. Our 4 exams will be worth about 125 each or 500 points total. The remaining will come from the assignments below. Please note that late submissions will lose points.

    ASSIGNMENT 1 - Notes to prepare for Jeopardy and Test 1. Due 1/29.
    Completion of this linked assignment is necessary to earn any Jeopardy points and will help you prepare for our first exam.
    ASSIGNMENT 2 - REQUIRED-Using Drug Info Resources Due 3/10. 75 pts I believe that everyone should know how to find information on the medications they or their loved ones are taking. Today's physicians rarely take the time to fully inform patients about their meds and often don't ask what other drugs, herbs, or supplements are being used. Pharmacists make mistakes. It is up to us to take an active role in monitoring our health care and watch out for ourselves - even if it means wading through some medical jargon. For this assignment you must find key information on prescription drug of your choice, using the Physician's Desk Reference and at least 1 other detailed general drug reference. If you don't have a medication in mind I'd suggest choosing one of the medications included in our text to get a head start on a drug category we will be covering.
    ASSIGNMENT 3 - REQUIRED- Critical evaluation of a OTC drug commercial or ad Due 4/14. 25 pts Videotape a drug commercial or copy a drug ad from a magazine, preferably one for one of the OTC analgesic or cold or allergy medications discussed in class. Using class information and drug references evaluate everything that is said, everything that seems to be suggested, the way the drug is portrayed or referred to, sale pitch, and the accuracy, honesty & completeness of the info presented. Is the manufacturer being totally straight forward with the consumer? Or does the ad mislead consumers with what it says, implies, or what it fails to say? Would you praise or "tsk tsk" their advertising?

    Graduate students will, in addition, be asked to prepare a review of 10 current research reports on a narrowly defined drugs topic (125 pts; handout will be provided). Keep Dr. Walsh up to date by telling me about the methods and findings of new research on a drugs topic. Please select and submit your preliminary computer search of research articles on a narrow topic by 3/5, show me 6 related primary sources no later than 4/7, and your completed papers by 4/28.

    Optional Assignment. Do a 2 day Addiction Simulation . This simulation is recommended for future teachers and is not recommended for anyone who has had a substance problem. It is only an educational experience if you commit to truly following the instructions. It does involve deceiving friends, family, and employers for the 2 day period. Due by 3/12.
    (up to 25 pts)

    Optional Assignment. Arrange to go out into the community (Waterloo-Cedar Falls or your hometown area) and interview an individual or individuals who are currently working living in areas affected by drug-use (police, substance abuse counselors, school counselors, health care providers, court officials are some that come to mind). Plan for your interview carefully, doing some reading to help prepare a good list of questions. Prepare a report on the individual(s), the setting, your questions, and the interview responses. If you feel you and your interviewee are up to it, a videotape of your "investigative report" could be an alternative.(up to 25 pts) Due by 4/23.

    10 pt Extra Credit. Keep a blank videotape handy to record any shows, segments, or news reports on the drugs/drug issues we cover in this class. Turn the tape in to me with a summary of the program , why you think it's relevant to the class, and a critical evaluation of the segment using an evaluation handout.(tape will be returned). May be done once for credit.  No later than 4/23.
     

  • Grading: Undergrads doing required assignments will have ~75% of their grade based on exams & ~25% based on assignments. Doing optional assignments changes this balance. Grades will be based on the total number of points accumulated during the semester. (Grad student will have additional readings and a lit review assignment worth 125 points.)
  • ***Must have a passing average on exams to pass the course - cannot pass on assignments only.
  • Your final course grade will be assigned according to this scale:
  •  
    Grade
    Percent
    Grade
    Percent 
    Grade
    Percent
    A
    93.0-100.0% 
    B-
    80.0 - 82.9%
    D+
    67.0 - 69.9% 
    A-
    90.0 - 92.9%
    C+
    77.0 - 79.9% 
    D
    63.0 - 66.9% 
    B+
    87.0 - 89.9%
    C
    73.0 - 76.9% 
    D-
    60.0 - 62.9% 
    B
    83.0 - 86.9% 
    C-
    70.0 - 72.9%
    F
    0.0 - 59.9%

    About Your Prof
    Birthplace: Chicago, Illinois
    Education: B.S. (Psychology) University of Illinois, Chicago;
                      M.A. (Biopsychology) University of Chicago;
                      Ph.D. (Biopsychology) University of Chicago
    Married:  James Walsh (attorney)
    Children:  3 girls (Jennifer, Sara, & Annie)
    Hobbies:  Gardening, gourmet cooking, travel, concert-hopping, reading
    Most unusual experiences: Performing brain surgery on rats, riding an elephant (twice!), climbing the Great Pyramid, wearing a live python around my neck, flying in a blimp, visiting ancient Greek ruins, giving birth
    Goals: Continue to learn for the rest of my life, enjoy my professional and private lives, help others discover psychology (especially the biological side of psychology)

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    This page was prepared by Linda Walsh, Dept. of Psychology,
    University of Northern Iowa, Cedar Falls, IA 50614-0505.
    Last updated  1/9/09