Drugs - Psychotherapeutic Medications
what does the monoamine theory of mood propose underlies
depression?
antidepressants
Tricyclic antidepressants (TCAs)
best known original TCAs:
currently used TCAs:
how do they affect CNS
neurotransmitter effect thought
to improve depression:
neurotransmitter effects that
cause side effects:
side effects
other risks
other uses besides treatment of depression
Monoamine oxidase inhibitors (MAOIs)
example of a MAOI:
newest, most promising form of
MAOI:
how do they affect CNS
what is monoamine oxidase
neurotransmitter effect thought
to improve depression:
What risk/problem is caused by MAO inhibitors?
What must patients using MAOIs do
to avoid this risk
What happens if they don't do
this?
other uses besides treatment of depression
Selective serotonin reuptake inhibitors (SSRIs)
best known original SSRI (generic
and brand names)
other examples:
how do they affect CNS
neurotransmitter effect thought
to improve depression:
side effects
other risks/problems of SSRIs
other uses besides treatment of depression
what is serotonin syndrome & its symptoms?
what are the symptoms of SSRI discontinuation or
withdrawal?
what are examples of currently popular antidepressants that don't fit
in the above categories and why might they be used
what changes in the monoamine theory of mood have been proposed as
explanations for the several week delayed effectiveness of all the
antidepressants?
what "black box warning" has been added to all PDR listings and package
inserts for antidepressants?
what is a herbal/dietary supplement for depression
how is it similar to the prescription meds for depression
Mood Stabilizers
best known drug for biopolar disorder:
what is unusual about its characteristics
side effects:
risks:
signs of lithium toxicity:
what must patient do to avoid
this risk:
besides this risk, what is a
complicating problem in the treatment of bipolar disorder with lithium
2 categories of drugs used as alternatives to lithium and examples of
each
what is the trend today (both in the treatment of depression and the
treatment of b ipolar disorder) if satisfactory results are not
obtained using one of the medications above?
Antipsychotics
other terms to refer to antipsychotic medications
what is the dopamine theory or hypothesis of
schizophrenia and what supports this proposal
Typical or First Generation Antipsychotics
phenothiazines
best known example (generic and
brand names)
most important side effects:
drug action on CNS that is
thought to improve the symptoms of schizophrenia:
drug actions on CNS that are
thought to cause the different side effects
different types of extrapyramidal
motor symptoms
what well known typical antipsychotic is from the family of
drugs called butyrophenones?
how is this drug somewhat different from the phenothiazines?
Atypical or Second Generation Antipsychotics
first and best known example (generic and brand
name):
other examples of atypicals:
drug action on the CNS:
how is this different from earlier antipsychotics
in what ways was this drug an improvement over the
typical antipsychotics?
major drawback of this drug:
major undesired side effects of other atypicals:
what is neuroleptic malignant syndrome?
other uses for "antipsychotic" medications